Research use only. For in-vitro and laboratory research. Not for human or veterinary use. No aliquoting guidance is provided.

CBL-514 Research Video Explainer

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This short video explains CBL-514 as a research compound. CBL-514 is Caspase-3 & Bax/Bcl-2 Ratio-Modulating Adipocyte Apoptosis Research Compound. It covers its molecular identity (CAS Proprietary Synthetic Small-Molecule / Peptidomimetic Reference, Batch COA Verified) and the pathways studied in laboratory models. For in-vitro and laboratory research use only. Not for human or veterinary use.

Identity

What researchers study it for

• Studying selective induction of intrinsic caspase-3 and Bax/Bcl-2 apoptotic pathways in mature adipocytes in vitro.
• Comparing non-necrotic programmed cell death (apoptosis) vs detergent-induced membrane lysis in adipose cultures.
• Investigating mitochondrial outer-membrane permeabilisation (MOMP) and cytochrome c release kinetics.

How it is studied to work

• 1. Bax / Bcl-2 Ratio Shift Up-regulates pro-apoptotic Bax relative to anti-apoptotic Bcl-2 in differentiated white adipocytes.
• 2. Mitochondrial Cytochrome c Efflux Triggers mitochondrial outer-membrane permeabilisation and apoptosome assembly via Apaf-1 and caspase-9.
• 3. Cleaved Caspase-3 Execution Activates executioner caspase-3 and PARP cleavage without triggering necrotic pro-inflammatory cytokine release.

Lab links

Verify your batch All peptide videos

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Corex Vitality™ supplies research peptides for laboratory use only. This page is an educational explainer of molecular identity and published research pathways. It is not medical advice and does not recommend human use.