Research use only. For in-vitro and laboratory research. Not for human or veterinary use. No aliquoting guidance is provided.

Mazdutide Research Video Explainer

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This short video explains Mazdutide as a research compound. Mazdutide is Dual GLP-1R & Glucagon Receptor (GCGR) Oxyntomodulin Analogue (IBI362). It covers its molecular identity (CAS 2259884-03-0, 4563.06 g/mol) and the pathways studied in laboratory models. For in-vitro and laboratory research use only. Not for human or veterinary use.

Identity

What researchers study it for

• Investigating balanced dual GLP-1 receptor (GLP-1R) and Glucagon receptor (GCGR) co-agonism in metabolic assays.
• Studying hepatic lipid oxidation, VLDL-triglyceride clearance and thermogenic energy expenditure pathways.
• Comparing oxyntomodulin-derived acylated peptide pharmacokinetics and albumin binding vs mono-agonists.

How it is studied to work

• 1. Dual GLP-1R + GCGR Binding Simultaneously engages class-B GPCRs GLP-1R (islet/CNS) and GCGR (hepatocyte/adipose) with balanced potency.
• 2. Gs / Adenylyl Cyclase / cAMP Cascade Elevates intracellular cAMP and activates PKA/EPAC2 across both incretin and glucagon receptor axes.
• 3. Hepatic Beta-Oxidation & Glycaemic Balance Drives hepatic fatty-acid oxidation and lipolysis while GLP-1R co-activation buffers hepatic glucose output.

Lab links

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Corex Vitality™ supplies research peptides for laboratory use only. This page is an educational explainer of molecular identity and published research pathways. It is not medical advice and does not recommend human use.