About PT-141 (Bremelanotide)
PT-141 (also known in published literature as Bremelanotide) is a synthetic cyclic lactam heptapeptide with the amino acid sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH. PT-141 is investigated in preclinical and receptor-binding studies for its selective interaction with central melanocortin receptors, particularly MC3R and MC4R. PubChem lists its molecular formula as C50H68N14O10, with a molecular weight of approximately 1025.2 g/mol (CAS 189691-06-3).
The product supplied by Corex Vitality™ is an analytical reference and laboratory research compound for in vitro research use only. Browse all batch certificates on our COA and verification page.
Product specifications
| Compound |
PT-141 (Bremelanotide) |
| Form |
Lyophilised (freeze-dried) powder in a sealed research vial |
| Size |
10mg (actual tested fill: 10.86mg per COA LDA22161262) |
| Sequence |
Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH |
| CAS Number |
189691-06-3 |
| Molecular formula |
C50H68N14O10 (PubChem) |
| Molecular weight |
1025.2 g/mol (PubChem) |
| Chromatographic Purity (HPLC) |
>99.63% ± 0.18% (View Batch COA LDA22161262) |
| Endotoxin & Sterility |
0.27 EU/mg (≤0.50 EU/mg spec) · Sterility: PASS (No growth) |
| Availability |
In stock — UK tracked dispatch (1–2 working days) |
Storage and handling
Storage & Handling — Corex Vitality™ research vials
- As supplied: freeze-dried (lyophilised) powder in a sealed vial. Room-temperature transit is normal for dry peptides.
- Longer storage: keep the vial tightly closed in a freezer at −20 °C or colder, dry and away from light. Colder is better for long archives.
- Short-term: a laboratory fridge (2–8 °C) is fine for vials you plan to open soon.
- Before opening: let the closed vial warm to room temperature, ideally in a desiccator, so moisture does not condense on the powder. Work quickly and reseal tightly; absorbed moisture lowers the real peptide content.
- Dissolving: choose a solvent based on the sequence (see the compound note below) and test a small portion first. Swirl gently; brief sonication in a water bath can help. Do not heat.
- Once in solution: make up only what you need. Split any solution you keep into single-use aliquots, freeze at −20 °C or colder and thaw each aliquot only once. Peptides keep far less well in solution than as dry powder.
- Safety: handle in a suitable laboratory with appropriate PPE, following your institution’s safety procedures, and avoid breathing the powder. Keep out of reach of children.
Compound note: Oxidation-sensitive: cyclic peptide containing tryptophan, which is light- and oxidation-sensitive. Protect from light and use degassed solvent. Basic: a trace of dilute acetic acid before dilution if needed.
For in-vitro laboratory research use only. Not for human or veterinary use. General guidance paraphrased from Bachem: Handling and Storage Guidelines for Peptides and Peptide Solubility.
Quality and testing
The published PT-141 10mg batch COA (Lingda Laboratory, Report No. LDA22161262) reports HPLC-UV/VIS purity and quantity, heavy metals (ICP-MS), endotoxin (LAL assay) and sterility results. You can inspect the full Certificate of Analysis directly via the PT-141 10mg Batch COA (Report No. LDA22161262) or search by report number on our COA Verification page.
Research use only
For in-vitro laboratory research use only. Not for human or veterinary use. These products are research chemicals. They are not medicines, food, or supplements. They have not been evaluated by the MHRA, FDA, or any other regulatory body. Not intended to diagnose, treat, cure, or prevent any disease. All descriptions are for reference and research documentation purposes only. By purchasing, you confirm you are aged 18+ and using these products exclusively for in vitro laboratory research.
